Relationship between interleukin-6 levels and periodontal status of patients with insulin dependent diabetes mellitus and chronic periodontitis

The aim of the present study was to determine interleukjn-6 [IL-6] levels in gingival crevicular fluid [GCF] and serum and to compare the levels with clinical periodontal findings in patients with diabetes mellitus [DM] and chronic periodontitis [CP]. A total of 30 patients were divided into 3 groups [10 patient with DM and CP, 10 patients with CP and 10 healthy controls] Gingival index [GI] and pocket dopth [PD] values for each CP patients were recorded. Enzyme linked immunosorbent assay for quantitative detection of IL-6 in each GCF and serums sample was employed. Significant difference was detected between all groups with the lowest level of GCF IL-6 in DM/CP. However various IL-6 levels were detected in the serum of DM/CP group which failed to be assayed for CP and control group. No strong correlation could be detected between GCF IL-6 level and GI score or PD values. The finding of the present study suggests that IL-6 should not be considered as just an inflammatory mediator aiding in tissue destruction but it posses a pivotal role in tissue homeostasis To our knowledge this study is the first report correlating IL-6 levels in insulin dependent diabetes mellitus to their clinical periodontal data

Ectopic pregnancy: 5 year experience in Saudi German hospital, Saudi Arabia

The aim of this study was to assess the prevalence of ectopic pregnancy, the possible risk factors, presentations, different modalities of diagnosis, role of laparoscopy in the management and the follow up after conservative laparoscopic surgery. The study showed that the rate of ectopic pregnancy was 1.8% of the live births, salpingitis was the most common risk factor and was found in 40% of the patients. 85% of the patients were symptomatic but clinically stable or asymptomatic. 80% of the cases were diagnosed by transvaginal sonography, 95% of the patients by laparoscopy and 80% of the laparoscopic operations were conservative